Nature

Generative and predictive neural networks for the design of functional RNA molecules

We evaluated a CNN’s ability to convert our structural array into interpretable structural information using a simulated dataset of toehold switches and several decoy sequences (Fig. 2a). Toehold ...
Nature

Expanding functional protein sequence spaces using generative adversarial networks

A protein’s three-dimensional (3D) structure, physicochemical properties and molecular function are defined by its amino-acid sequence. From the 20 commonly occurring proteinogenic amino acids, a ...