Epistasis arises when alleles at one locus modify the phenotypic expression of alleles at another, generating non-additive contributions to trait variation. In natural populations, genetic variance ...

A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased ...

A sweeping genomic analysis reveals how psychiatric disorders cluster into five biological families, exposing shared pathways and pinpointing where their genetic roots diverge. Study: Mapping the ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

A new study suggests that the long-standing Mendelian view of genetics has some blind spots.

Are human beings as unique as snowflakes? Not quite, but new research shows humans may have a lot more individuality than originally thought -- in fact, the genetic codes of people can vary by as much ...

Depression is a highly common mental health condition that affects millions of people worldwide. Medical professionals have ...

New research in the journal Science by Maxwell postdoctoral scholar Dustin Hill, Professor of Public Health Dave Larsen and a ...

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images Sitting in my doctor’s examination room, I was surprised when she ...