Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Imagine building a traffic surveillance camera that could detect trouble-making cells speeding around in your brain before their cellular gang could commit "crimes." Most importantly, this camera ...

This article describes a six-inch wafer inspection microscope that provides automated, reproducible differential interference contrast (DIC) imaging, regardless of the user’s skill level. Wafer ...

Processes in the human body are shaped by the interaction of various biomolecules, such as proteins and DNA. These processes take place in a range of often just a few nanometers. They can therefore no ...